M Lavigne Selected Research

licofelone

6/2005

The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.

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M Lavigne Research Topics

Disease

3	Osteolysis 05/2011 - 07/2007
2	Infections 11/2013 - 05/2013
1	Neoplasms (Cancer) 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2020
1	Pain (Aches) 05/2013
1	Femoracetabular Impingement 05/2011
1	Necrosis 05/2011
1	Osteopetrosis 06/2006
1	Hip Osteoarthritis (Coxarthrosis) 06/2006
1	Osteoarthritis 06/2005
1	Inflammation (Inflammations) 12/2001

Drug/Important Bio-Agent (IBA)

3	MetalsIBA 11/2013 - 06/2006
2	Polyethylene (Polythene)IBA 05/2011 - 07/2007
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020
1	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 06/2005
1	licofeloneIBA 06/2005
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 06/2005
1	2- (4- (quinolin- 2- yl- methoxy)phenyl)- 2- cyclopentylacetic acidIBA 06/2005
1	OxygenasesIBA 06/2005
1	Transcription Factors (Transcription Factor)IBA 06/2005
1	Matrix Metalloproteinases (MMPs)IBA 06/2005
1	Metalloproteases (Metalloproteinases)IBA 06/2005
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 06/2005
1	Interleukin-1beta (Interleukin 1 beta)IBA 06/2005
1	N-Formylmethionine Leucyl-PhenylalanineIBA 12/2001
1	spinorphinIBA 12/2001

Therapy/Procedure

2	Arthroplasty 12/2008 - 06/2006
1	Drug Therapy (Chemotherapy) 01/2020
1	Reoperation 05/2011
1	Conservative Treatment 05/2011
1	Hip Prosthesis 12/2008